Amphetamine, dextroamphetamine, methamphetamine, and their various salts are collectively referred to as amphetamines. In fact, their chemical properties and actions are so similar that even experienced users have difficulty knowing which drug they have taken. Methamphetamine is the most commonly abused.

Street terms for methamphetamine: Meth, poor man's cocaine, crystal meth, ice, glass, speed¹

• Injecting
• Snorting
• Smoking
• Oral ingestion ²

• During 2000, 4% of the U.S. population reported trying methamphetamine at least once in their lifetime.³
• Abuse is concentrated in the western, southwestern, and midwestern United States.

• Clandestine laboratories in California and Mexico are the primary sources of supply for methamphetamine available in the United States.
• Domestic labs that produce methamphetamine are dependent on supplies of the precursor chemical pseudoephedrine, which is sometimes diverted from legitimate sources. It is smuggled from Canada, and to a lesser extent from Mexico.
• Domestic independent laboratory operators, mostly in the western, southwestern, and midwestern United States, also produce and distribute methamphetamine but on a smaller scale.
• Yaba (meth in tablet form) is most often produced in Southeast Asia and sent by mail or courier to the United States.⁴

• Prices for methamphetamine vary throughout different regions of the United States.
• At the distribution level, prices range from $3,500 per pound in parts of California and Texas to $21,000 per pound in southeastern and northeastern regions of the country. Retail prices range from $400 to $3,000 per ounce.⁵

• Effects of usage include addiction, psychotic behavior, and brain damage .⁶
• Withdrawal symptoms include depression, anxiety, fatigue, paranoia, aggression, and intense cravings. ⁷
• Chronic use can cause violent behavior, anxiety, confusion, insomnia, auditory hallucinations, mood disturbances, delusions, and paranoia. ⁸
• Damage to the brain cause by meth usage is similar to Alzheimer's disease, stroke, and epilepsy.⁹

1Office of National Drug Control Policy, Street Terms: Drugs and the Drug Trade.
²Drug Enforcement Administration,The Forms Of Methamphetamine, April 2002
³Substance Abuse and Mental Health Services Administration, Summary of Findings from the 2000 National Household Survey on Drug Abuse, September 2001.
⁴Drug Enforcement Administration, Drug Trafficking in the United States, September 2001.
⁵Ibid.
⁶Office of National Drug Control Policy, Drug Facts: Methamphetamine, May, 2002.
⁷Ibid.
⁸Ibid.
⁹National Institute on Drug Abuse, Methamphetamine: Abuse and Addiction, April, 1998. What are the Effects of Methamphetamine Abuse?

Information on this page came primarily from the Drug Enforcement Administration at www.dea.gov

Methamphetamine

Systematic (IUPAC) name
N-methyl-1-phenylpropan-2-amine
Identifiers
CAS number	537-46-2
ATC code	N06BA03
PubChem	CID 1206
DrugBank	DB01577
ChemSpider	1169
Chemical data
Formula	C10H15 N
Mol. mass	149.233 g/mol
SMILES	eMolecules & PubChem
Synonyms	Desoxyephedrine Pervitin Anadrex Methedrine Methylamphetamine Syndrox Desoxyn
Pharmacokinetic data
Bioavailability	62.7% oral; 79% nasal; 90.3% smoked; 99% rectally; 100% IV
Metabolism	Hepatic
Half-life	9–15 hours[1]
Excretion	Renal
Therapeutic considerations
Pregnancy cat.	C(US)
Legal status	Controlled (S8) (AU) Schedule I ( CA) Schedule II ( US) Class A( NZ) Schedule 5(SA) Injectable:Class A, Oral: A(UK)
Routes	Medical: Oral Recreational: Oral, I.V., I.M., Insufflation, Inhalation, Rectal
Y (what is this?)  (verify)

Methamphetamine (pronounced /ˌmɛθæmˈfɛtəmiːn/ listen), also known as metamfetamine (INN), dextromethamphetamine, methylamphetamine, N-methylamphetamine, desoxyephedrine, and colloquially as meth (not to be confused with methadone, sometimes referred to as "meth" by opioid users, or with mephedrone, sometimes referred to as "meph"), is a psychoactive stimulant ( psychostimulant or psychoanaleptic) drug of the phenethylamine and amphetamine chemical classes. It increases alertness, concentration, energy, and in high doses, can induce euphoria, enhance self-esteem, and increase libido. ^{[2] [3]} Methamphetamine has high potential for abuse and addiction by activating the psychological reward system via increasing levels of dopamine, norepinephrine and serotonin in the brain. Methamphetamine is approved by the U.S. Food and Drug Administration (FDA) for the treatment of attention-deficit hyperactivity disorder (ADHD) and exogenous obesity. Methamphetamine is marketed in the United States under the trademark name Desoxyn.^[4]

Methamphetamine

Systematic (IUPAC) name
N-methyl-1-phenylpropan-2-amine
Identifiers
CAS number	537-46-2
ATC code	N06 BA03
PubChem	CID 1206
DrugBank	DB01577
ChemSpider	1169
Chemical data
Formula	C10 H15N
Mol. mass	149.233 g/mol
SMILES	eMolecules & PubChem
Synonyms	Desoxyephedrine Pervitin Anadrex Methedrine Methylamphetamine Syndrox Desoxyn

Methamphetamine (pronounced /ˌˌmeth-am-ˈfet-ə-ˌmēn, ˌmeth-əm-, -mən/ listen), also known as metamfetamine (INN), dextromethamphetamine, methylamphetamine, N-methylamphetamine, desoxyephedrine, and colloquially as meth (not to be confused with methadone, sometimes referred to as "meth" by opioid users, or with mephedrone, sometimes referred to as "meph"), is a psychoactive stimulant (psychostimulant or psychoanaleptic) drug of the phenethylamine and amphetamine chemical classes. It increases alertness, concentration, energy, and in high doses, can induce euphoria, enhance self-esteem, and increase libido.^[2][3] Methamphetamine has high potential for abuse and addiction by activating the psychological reward system via increasing levels of dopamine, norepinephrine and serotonin in the brain. Methamphetamine is approved by the U.S. Food and Drug Administration (FDA) for the treatment of attention-deficit hyperactivity disorder (ADHD) and exogenous obesity. Methamphetamine is marketed in the United States under the trademark name Desoxyn.^[4]

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